Managing Nonmetastatic Castration-Resistant Prostate Cancer

Joaquin Mateo a, Karim Fizazi b, Silke Gillessen c, Axel Heidenreich d, Raquel Perez-Lopez a,
Wim J.G. Oyen e, Neal Shore f, Matthew Smith g, Christopher Sweeney h, Bertrand Tombal i,
Scott A. Tomlins j, Johann S. de Bono e,*

 

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Phase 1 Study of Seviteronel, a Selective CYP17 Lyase and Androgen Receptor Inhibitor, in Men with Castration-Resistant Prostate Cancer

Shilpa Gupta, Luke T Nordquist, Mark T Fleming, William R Berry, Jingsong Zhang, Sharon L Ervin, Joel R Eisner, Edwina S Baskin-Bey and Neal D Shore

“Enzalutamide in Men with Nonmetastatic, Castration-Resistant Prostate Cancer” appeared in NEJM • Neal Shore, MD among the contributing authors

The publication titled “Enzalutamide in Men with Nonmetastatic, Castration-Resistant Prostate Cancer” appeared in The New England Journal of Medicine online yesterday and will appear in the June 28 print edition. Click here to read

full article

Two associated articles, an Editorial titled “Progress in Nonmetastatic Prostate Cancerclick here to read

and a Perspective titled “Metastasis-free Survival — A New End Point in Prostate Cancer Trials” also appeared in the same issue of The New England Journal of Medicine. Click here to read

 

 

ASCO 2018: Latest developments in non-metastatic and metastatic castration-resistant prostate cancer

Dr Neal Shore is joined by Dr Simon Chowdhury, Prof Matthew Smith and Prof Boris Hadaschik at the 2018 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

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ASCO 2018: Novel treatment strategies in prostate cancer therapeutics

Dr Neal Shore speaks to Prof Karim Fizazi at ASCO 2018 about the changing landscape of treatments for prostate cancer, discussing immunotherapies, PARP inhibitors and PSMA testing as future targets and treatments.

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Absorbable Hydrogel Spacer Use in Prostate Radiotherapy: A Comprehensive Review of Phase 3 Clinical Trial Published Data

Neal D. Shore, Lawrence I. Karsh, Eric T. Gross, Christopher M. Pieczonka, Philip J. Aliotta, Christopher J. Skomra, Lee E. Ponsky,  Peter T. Nieh, Misop Han, Daniel A. Hamstra

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The Journal of Urology: Androgen Receptor–Targeted Treatments for Prostate Cancer: 35 Years’ Progress with Antiandrogens

• E. David Crawford, Paul F. Schellhammer, David G. McLeod, Judd W. Moul, Celestia S. Higano, Neal Shore, Louis Denis, Peter Iversen, Mario A. Eisenberger, Fernand Labrie

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The Future of Value-Based Care Relies Upon Providers: Taking the Reins on Alternative Payment Models

Dr. Shore, co -author

2017 was a pivotal year for the growth of value-based care. For many practices, this meant completing their first performance year as part of the Merit-Based Incentive Payment System (MIPS). A much smaller percentage of practices was able to participate in approved advanced Alternative Payment Models (APMs).

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Optimizing the treatment of metastatic castration‑resistant prostate cancer: a Latin America perspective

Dr. Shore, co -author

Prostate cancer is a significant burden and cause of mortality in Latin America. This article reviews the treatment options
for patients with metastatic castration-resistant prostate cancer (mCRPC) and provides consensus recommendations to
assist Latin American prostate cancer specialists with clinical decision making.

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A Revolutionizing Time in Immuno-Oncology for Bladder Cancer – Neal Shore

There has been a limited number of new therapeutics, particularly in the area of patients who would benefit from advanced systemic bladder cancer treatments. Dr. Neal Shore reviews some pioneering work from the past such as MVAC and gemcitabine platinum based combinations but he notes those treatments are where things were left for many many years. The development of immuno-oncology is revolutionizing how physicians should be thinking about bladder and renal cancer treatments.

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